The Epstein-Barr virus (EBV) nuclear proteins EBNA3A. EBNA3B. and EBNA3C interact with the cell DNA binding protein RBPJ and regulate cell and viral genes. Repression of the CDKN2A tumor suppressor gene products p16(INK4A) and p14(ARF) by EBNA3A and EBNA3C is critical for EBV mediated transformation of resting B lymphocytes into immortalized lymphoblastoid cell lines (LCLs). https://www.mypetfoodcenters.shop/product-category/litter-boxes/