Gasdermin-D (GSDMD) is the ultimate effector of pyroptosis. a form of programmed cell death associated with pathogen invasion and inflammation. After proteolytic cleavage by caspases. the GSDMD N-terminal domain (GSDMDNT) assembles on the inner leaflet of the plasma membrane and induces the formation of membrane pores. https://thebrickes.shop/product-category/pond-accessories/