Neuropeptide- and hormone-containing secretory granules (SGs) are synthesized at the trans-Golgi network (TGN) as immature secretory granules (ISGs) and complete their maturation in the F-actin-rich cell cortex. This maturation process is characterized by acidification-dependent processing of cargo proteins. condensation of the SG matrix and removal of membrane and proteins not destin... https://fitnessgravesyardes.shop/product-category/shaft-assembly/
Rab3D is critical for secretory granule maturation in PC12 cells.
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