Background and Objective: Pain is a common postoperative complaint. and the use of analgesics before surgical trauma can effectively prevent peripheral and central sensitization. We aimed to compare the preemptive effects of ibuprofen and celecoxib on post-operative pain after lower abdominal surgery in addicted patients. Materials and Methods: In this clinical trial. https://parisnaturalfoodes.shop/product-category/stop-smoking-help/