Background: Interaction of the programmed death receptor 1 (PD-1) and its ligand. PD-L1. suppresses T cell activity and permits tumors to evade T cell-mediated immune surveillance. We have recently demonstrated that antigen-specific CD8+ T cells transduced with a PD1-CD28 fusion protein are protected from PD-1-mediated inhibition. https://jalyttlers.shop/product-category/frying-pans/