Linker for activation of T cells (LAT) is a central adaptor protein in proximal T cell activation. A key element of its adaptor function is the efficiency with which LAT interacts with its binding partners. Such efficiency is controlled by the local concentration of LAT as well as the vicinity to up- and downstream interaction partners. i. https://www.roneverhart.com/HGST-Ultrastar-7K6000-HUS726040ALS214-4TB-7-2K-RPM-SAS-12Gb-s-512n-128MB-3-5-SE-Hard-Drive/